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 >>  . C 01.02.00
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615.454.2:615.07 . . , . . , . . , - . , ., . . , . . , , . ...

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Key words: stability, pessaries, metronidazole, oil of tea tree, gas chromatography, absorbing spectrophotometry

   

With the purpose of standardization of combined pessaries Melanizole was conducted development of methodologies of quantitative determination of active substances: metronidazole and components of tea tree oil.

Research of basic quality indexes of pessaries Melanizole was conducted in accordance with the requirements of SPhU. On the base of the obtained data a project of MCQ was worked out.

Conditions and terms of storage of samples of pessaries was also investigated. It has been determined that at storage in a cold or cool place under temperature from 8 C to 15 C pessaries kept the quality indexes during two years and answered the requirements of project MCQ.



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