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1. Aronson D., Rayfield E.J., Chesebro J.H. Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction. Ann. Intern. Med. 1997; 126: 296306.

2. Lee K.L., Woodlief L.H., Topol E.J. et al. Predictors of 30day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-1 Investigators. Circulation 1995; 91: 1659. 68.

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4. .. . Consilium Medicum Ukraina. 2008; 2: 4446.

5. Cottina Y., Lhuillier I., Gilsonb L., Zeller M. Glucose insulin potassium infusion improves systolic function in patients with chronic ischemic cardiomyopathy. Eur. J. of Heart Failure 2002; 4: 181184.

6. Iwan C.C. van der Horst, Jan P. Ottervanger, Arnoud W.J.vant Hof, Stoffer Reiffers at al. Glucose-insulin-potassium infusion in acute myocardial infarction on infarct size and left ventricular ejection fraction BMC Medicine 2005, 3: 9.

7. Van der Horst I.C., Zijlstra F., vant Hof A.W. et al. Glucose-insulin-potassium infusion in patients treated with primary angioplasty for acute myocardial infarction: the glucose-insulin-potassium study: a randomized trial. J. Am. Coll. Cardiol.

2003, 42: 784791.

8. Pache J., Kastrati A., Mehilli J. et al. A randomized evaluation of the effects of glucose-insulin-potassium infusion on myocardial salvage in patients with acute myocardial infarction treated with reperfusion therapy. Am. Heart J. 2004, 148: 105.

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SPECIFICS OF CORRECTIONAL METAbOLIC THERAPY IN PATIENTS wITH ACUTE MYOCARDIAL




140 .


INFARCTION wITH DIAbETES MELLITUS

Prikhodko N.P., Shaposhnik O.A.

Summary. There were examined 51 patients with acute myocardial infarction, including 26 with diabetes mellitus for determining the specifics of metabolic therapy by glucose-insulin-potassium in patients with acute myocardial infarction and type 2 diabetes mellitus. It was found that the severity of acute heart failure by Killip and cardiogenic shock in patients with acute myocardial infarction greater in patients with diabetes mellitus. It is justified to use glucose-insulin-potassium in patients with acute myocardial infarction and type 2 diabetes mellitus, particularly in view of its antiarrhythmic effect. GIK infusion had no significant effect on blood glucose levels, which may indicate the safety of such ratios of glucose, insulin and potassium chloride.

Keywords: acute myocardial infarction, diabetes mellitus, glucose-insulin-potassium (GIK).

:

. 23, . , 36024 . (0532) 22-42-45 : np.prikhodko@mail.ru



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