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, 2010, 4 35 547.466: 578/ 579: 620.169.462.21: 616 005.6: 612.6.052.4 .. ...

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, 2010, 4 35

547.466: 578/ 579: 620.169.462.21: 616 005.6: 612.6.052.4

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, H2S , 677 MTHFR .

. ( ) . 148 , 2076 ( 53,41,06 ), 83 (56,1%) , 57 (38,5%) . . 82 20 74 (50,21,28 ), 42 (51,2%) .., 2010 36 , 2010, 4 . , (, , ), , , , 2 1. , . , 㳺 0108U008139.

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MTHFR 677 ( V G1691A (FV Leiden) F G20210) Genotyping kit Venous Thrombosis (Technoclone, ). г Homocysteine EIA (Axis Shield, ). [10]. H2S 1% 1:5 1 ( FeCl3) [7].

, [2, 12]. г 10 , 1015 , 15 (). г 300 , 300350 , 350 ().

MS Exel XP Statistica SPSS 10.0 for Windows. t , ϳ, F Գ, . (odds ratio OR) 95% (I confidence interval) [3]. 0,05.

m.

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ǒ, . , 2 (2,4%) FV G1691A Leiden 1 (1,2%) F G20210, 24 (16,2%) 10 (6,8%) FV Leiden F G20210. . MTHFR (28,7% 29,7%). 35,4% (29 ) , 2010, 4 37 11,0% (9 ) , 35,1% (52 ) 12,2% (18 ) . , 7,4% (11 ) : 1 GA FV Leiden + GA F, 8 GA FV Leiden + MTHFR, 2 MTHFR + GA F.

, . FV Leiden, F G20210 677 MTHFR [14].

, ³ , (27,4%) [4].

FV Leiden F G20210, . , , H2S 79 113 .

(. 1), , , 40,4%. , , , 39,8% ( 12,6% ). . г MTHFR , . ,

   

( 61,4%), ( ), . ǒ, ( , ) , 쳺. . MTHFR .

17,3% , (. 2). , . 쳿 6 (7,6%) 34 (30,0%) . ϳ MTHFR.

   

, H2S (, ). , H2S 25,4% , (. 3). , 80% H2S 6594 (1090 ) 5% 62 (5 ), , 80% H2S , 2010, 4 39

   

4679 (1090 ) 5% 42 . H2S (/H2S /H2S), . H2S ( , ), 1012% , /H2S /H2S, , , .



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