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ISSN 2079-8334. 㳿. 2014. 1(43) 12. Olbe L. Effect of omeprazole on gastric acid secretion and plasma gastrin in man / L. Olbe, C. Cederberg, T. Lind [et al.] ...

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. 1. Na+,K+-- . 2. Ca2+,Mg2+-- () () , %. , %.

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, , SERCA. Na+,K+-- Ca2+,Mg2+-- Na+ Ca2+ , , Ca2+,Mg2+-- Ca2+ [15].

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, , [8,12] , ISSN 2079-8334. 㳿. 2014. 1(43) , 㳿, .

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2. Na+,K+-- Ca2+,Mg2+-- Na+ Ca2+ , .

3. .

1. .. / ..

, .. , .. [ .] // ˳. 2006. 3-4. . 43-46.

2. .. : / .. , .. // , . 2012. - 4. . 49-51.

3. .. / .. , .. // . ., - 1965. . 106-112.

4. .. / .. , ..

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12. Kowalski R.J. Immunodiagnostics: evaluation of functional T-cell immunocompetence in whole blood independent of circulating cell numbers / R. Kowalski, A. Zeevi, R. Mannon [et al.] // J. Immunotoxicol. 2007. Vol. 4, N 3. P. 225-232.

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P. 2403-2410.

ION AND ENERGY HOMEOSTASIS IN

PERIPHERAL BLOOD LYMPHOCYTES IN RATS

AT DERMATITISES

.. Cheremisina V.F.

We studied disorders of energy homeostasis and - ion saponin-perforated peripheral blood lymphocytes in rats with dermatitis of various etiologies. Shown that , stimulation of lymphocyte antigen triggers a cascade of , energy-dependent processes, which lead to a redistribution ; of macroergs in the cell, and this is associated with a Na+,K+--significant decrease oubain sensitive Na+,K+--ase and Ca2+,Mg2+-- , Ca2+,Mg2+--ase activity, a decrease in the pool of ATP . , in lymphocytes. Proved that with dermatitis of various , etiologies, especially allergic nature, violated regulatory Na+ Ca2+, mechanisms in lymphocytes by overloading cells Na+ and Ca2+, which leads to energy deficit lymphocytes and a . violation of their functional activity.

, , : Key words: homeostasis, lymphocytes, , . peripheral blood, and allergic contact dermatitis.

08.01.2014 . ..



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